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原发性胆汁性肝硬化(PBC)是一种起因不明的、肝内小胆管渐进性和不可逆性的自身免疫损伤形成的胆汁淤积性肝脏疾病。近年来的研究表明该病发病率呈逐年上升趋势,晚期患者可致肝硬化、肝癌及肝衰竭,严重威胁其身体健康。随着实验诊断技术的不断提高及实验室检测指标的广泛应用,将对PBC的早期诊断和及时治疗提供重要帮助。
Primary biliary cirrhosis (PBC) is a cholestatic liver disease of unknown origin with progressive and irreversible autoimmune damage in the intrahepatic bile ducts. In recent years, studies have shown that the incidence of the disease showed an upward trend year by year, patients with advanced liver cirrhosis can cause, liver cancer and liver failure, a serious threat to their health. With the continuous improvement of laboratory diagnostic techniques and laboratory tests widely used indicators will be of early diagnosis and timely treatment of PBC provide important help.