患儿男,11岁。全身泛发黑色斑疹8年。患儿为足月顺产,父母非近亲结婚。3岁时无明显诱因面部出现粟粒至黄豆大黑色斑疹,斑疹数量随年龄增大明显增加,渐波及颈部、躯干及上肢。夏季面部皮损无明显色素加深,无明显自觉症状。家族中无类似疾病者,也无其他遗传病史。患儿饮食、发育及智力与同龄儿童无明显差异。一般 Children male, 11 years old. General black hair rash 8 years. Children with full-term spontaneous birth, parents marry non-relatives. 3 years old no obvious incentive facial miliary soybeans large black spotted, the number of spotted increased significantly with age, gradually spread to the neck, trunk and upper limbs. No obvious pigmentation in summer facial lesions, no obvious symptoms. No similar family disease, nor other genetic history. Children with diet, development and intelligence and children of the same age no significant difference. general