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目的:观察氨溴索对ICU内机械通气患者肺部感染的临床疗效。方法:将广西医科大学第四附属医院中心ICU内呼吸机相关性肺炎患者62例随机分为两组,均行气管插管切开,应用有创呼吸机辅助通气,并对症支持治疗;观察组加用氨溴索注射液60 mg静脉滴注。结果:观察组在化痰排痰、抗炎抑菌及缩短机械通气时间方面疗效均优于对照组。结论:氨溴索对呼吸机相关性肺炎有良好辅助治疗作用。
Objective: To observe the clinical effect of ambroxol on pulmonary infection in patients with mechanical ventilation in ICU. Methods: Sixty-two patients with ventilator-associated pneumonia in the ICU of the Fourth Affiliated Hospital of Guangxi Medical University were randomly divided into two groups. All patients underwent endotracheal intubation and assisted ventilation with invasive ventilator. The patients in the observation group Plus ambroxol injection 60 mg intravenously. Results: The curative effect of observation group on sputum expectoration, anti-inflammatory and anti-bacterial and shortening mechanical ventilation time were better than the control group. Conclusion: Ambroxol has a good adjuvant therapy for ventilator-associated pneumonia.