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5. Novel cyclen-based linear polymer as a high-affinity binding material for DNA condensation

Novel cyclen-based linear polymer as a high-affinity binding material for DNA condensation

来源 :中国科学：化学英文版 | 被引量 : 0次 | 上传用户：bb1206

【摘 要】

：

A novel cyclen-based linear polyamine (POGEC) was designed and synthesized from the reaction between 1,3-propanediol diglycidyl ether and 1,7-bis(diethoxyphosph

【作 者】

：

YongZhe Xiang (1)  Na Wang (1 

【机 构】

：

1.KeyLaboratoryofGreenChemistryandTechnologyofMinistryofEducation,2.KeyLaboratoryofBio-resourcesandE

【出 处】

：

中国科学：化学英文版

【发表日期】

：

2009年4期

【关键词】

：

CYCLEN (1 4 7 10-tetraazacyclododecane) POLYAMINE POLYPLEX DNA CONDENSATION cycl 

【基金项目】

：

Supported by the National Natural Science Foundation of China (Grant Nos. 20725206 and 20732004),Specialized Research Fund for the Doctoral Program of Higher Education,Scientific Fund of Sichuan Provi

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论文部分内容阅读

A novel cyclen-based linear polyamine (POGEC) was designed and synthesized from the reaction between 1,3-propanediol diglycidyl ether and 1,7-bis(diethoxyphosphory)-1,4,7,10-tetraazacyclod-odecane. High-affinity binding between POGEC and DNA was demonstra

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