罗式易位是常见的染色体结构异常 ,在新生儿中的出现率为 1/ 10 0 0 [1] 。患者由于在减数分裂时可形成不平衡配子 ,因而常伴随不育、反复自然流产、死胎或生育染色体异常后代。通过观察出生儿的染色体情况得到的统计数字不能完全反映其配子生成的染色体分离规律 ,因为有一部分 Rollo-type translocation is a common chromosomal structural abnormalities, the incidence of neonatal 1/100 [1]. Patients with infertility, recurrent spontaneous abortion, stillbirth or chromosomal abnormalities due to unbalanced gametes during meiosis. The statistics obtained by observing the chromosomal status of an infant do not fully reflect the chromosome segregation rules generated by their gametes as a fraction