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目的总结近年来乳腺黏液癌(MBC)的最新研究进展。方法搜集MBC的相关文献,就乳腺黏液癌的定义、分类、分子生物学指标、淋巴结转移、预后等方面进行综述。结果 MBC是浸润性乳腺癌的一种特殊类型。依据黏液成分在肿物中的比例,将MBC分为单纯型黏液癌(PMBC)和混合型黏液癌(MMBC)。相较于非特殊型浸润性导管癌(IDC-NOS),MBC的雌激素受体(ER)和孕激素受体(PR)表达阳性率均较高,淋巴结转移少,生存率高,预后好。相较于MMBC,PMBC的淋巴结转移率低,预后好。结论 MBC与IDC-NOS的临床病理特征存在差异,是一种预后相对良好的病理学类型。
Objective To summarize the latest research progress of breast mucinous carcinoma (MBC) in recent years. Methods The relevant literature of MBC was collected to review the definition, classification, molecular biological indicators, lymph node metastasis and prognosis of breast mucinous carcinoma. Results MBC is a special type of invasive breast cancer. Based on the proportion of mucus in the mass, MBC was divided into simplex mucinous carcinoma (PMBC) and mixed mucinous carcinoma (MMBC). Compared with nonspecific invasive ductal carcinoma (IDC-NOS), the expression of estrogen receptor (ER) and progesterone receptor (PR) in MBC were higher than those in non-special type of invasive ductal carcinoma, with less lymph node metastasis, higher survival rate and better prognosis . Compared with MMBC, PMBC lymph node metastasis rate is low, the prognosis is good. Conclusion The clinicopathological features of MBC and IDC-NOS are different, which is a relatively good prognosis pathological type.