论文部分内容阅读
大剂量氨甲喋 配合甲酰四氢叶酸钙解救疗法(简称HD-MTX-CFR疗法)已证明对MTX一般剂量和其它化疗药物不大敏感的肿瘤如骨肉瘤等,能取得良好的疗效。我院于1982年S月至1983年6月用此疗法并同时作血中MTX浓度监测,治疗10例晚期非何杰金氏淋巴瘤,现报道如下: 一、一般资料: 男性5例,女性6例。年龄最小18岁,最大60岁,中位32岁。发病至治疗时间为4月至4年半,平均一年。临床分期按1971年Ann Arbor国际分期:ⅢA1例,ⅡA3例(广泛腹腔侵犯),
High-dose methotrexate with levofloxacin rescue therapy (HD-MTX-CFR therapy) has been shown to MTX general dose and other chemotherapy drugs are not sensitive to tumors such as osteosarcoma, can achieve good results. Our hospital from 1982 to June 1983 with this therapy and at the same time for blood MTX concentration monitoring, treatment of 10 cases of advanced non-Hodgkin’s lymphoma, are reported as follows: First, the general information: 5 males and females 6 cases. The youngest 18 years old, the oldest 60 years old, the median 32 years old. The onset of treatment time for April to 4 and a half years, an average of one year. Clinical staging according to 1971 Ann Arbor international staging: Ⅲ A1 cases, Ⅱ A3 cases (extensive abdominal invasion),