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根据流体动力学平衡系统(hydro dyna-mically balanced system,简称 HBS)原理,研制了美多心安 HBS 片(M-HBS片),以延长其在胃内的滞留时间,提高药物的生物利用度。为此,对 M-HBS 片的制备工艺、体外溶出试验及其在人体内的动态与进口缓释
According to the principle of hydro dyna-mically balanced system (HBS), M-HBS tablets (M-HBS tablets) were developed to prolong the residence time in the stomach and improve the bioavailability of the drug. To this end, the preparation of M-HBS tablets, in vitro dissolution test and its dynamics in the human body and imported sustained release