论文部分内容阅读
目的 探讨充血性心力衰竭患者甲状腺激素异常变化及临床意义。方法 采用放射免疫法检测了 6 4例充血性心力竭 (CHF)患者及 2 8例正常对照者血浆三碘甲状腺原氨酸 (T3 )四碘甲状腺原氨酸 (T4)、反三碘甲状腺原氨酸 (rT3 )及促甲状腺激素 (TSH)的浓度 ,并对CHF患者作了为期 6周的预后观察。结果 CHF患者T3 降低 ,rT3 升高 ,而T4、TSH正常。而且T3 越低 ,T3 /rT3 比值越小 ,心功能愈差 ,预后越差。结论 CHF患者T3 、尤其是T3 /rT3 比值的变化可作为病情程度及短期预后的判断指标。
Objective To investigate the changes of thyroid hormone in patients with congestive heart failure and its clinical significance. Methods Sixty-four patients with congestive heart failure (CHF) and 28 normal controls were enrolled in this study. Plasma triiodothyronine (T3), triiodothyronine (T4), anti-triiodothyroid Arginine (rT3) and thyroid stimulating hormone (TSH) concentrations in patients with CHF for a 6-week prognosis. Results T3 patients with CHF decreased, rT3 increased, while T4, TSH normal. And lower T3, T3 / rT3 ratio is smaller, worse heart function, the prognosis worse. Conclusion The changes of T3, especially the ratio of T3 / rT3 in CHF patients can be used as indicators to judge the degree of illness and short-term prognosis.