论文部分内容阅读
用人型结核杆菌Ｈ３７ＲＶ标准株皮下感染豚鼠，造成豚鼠结核病模型。瘰疬宁胶囊剂能使结核病豚鼠体重降低百分率明显减小；高、中两个剂量组豚鼠颈部肿大的淋巴结数目明显少于阴性对照组；该药还可减轻其脾、肺、肝的病变程度（肉眼观察）和脾、肺、肝、淋巴结的重量指数；病理检查发现，该药可使脾、肺、肝、淋巴结的干酪性坏死发生率显著降低；并能减少脾、肺、肝及淋巴结结核杆菌培养的活菌单位数目。
Guinea pigs were subcutaneously infected with the human-type Mycobacterium tuberculosis H37RV standard strain, resulting in a guinea pig tuberculosis model. Qionglaining Capsule can significantly reduce the percentage of body weight loss in tuberculosis guinea pigs; the numbers of enlarged lymph nodes in the neck of guinea pigs in high and middle dose groups were significantly less than those in the negative control group; the drug could also reduce the spleen, lung and liver Pathological examination revealed that the drug could significantly reduce the incidence of caseous necrosis of the spleen, lung, liver and lymph nodes, and reduce the incidence of spleen, lung and liver And the number of viable cells cultured with Mycobacterium tuberculosis.