本文对81例新生儿(足月儿43例,早产儿38例)早期血钠、钾和醛固酮的变化进行了动态观察。足月儿血钠、钾平均值分别为136.41±5.60mEq/L和5.73±0.65mEq/L,早产儿分别为135.92±5.72mEq/L和5.80±0.70mEq/L,两者差异无显著意义(P>0.05)。与成人相比,新生儿血钠低于而血钾高于成人。新生儿血醛固酮水平约为成人的9～10倍。新生儿早期血钠低而血钾高并非由于醛固酮分泌不足所致。 In this paper, the changes of serum sodium, potassium and aldosterone in 81 newborn infants (43 full-term infants and 38 preterm infants) were observed. The full-term serum sodium and potassium levels were 136.41 ± 5.60 mEq / L and 5.73 ± 0.65 mEq / L, respectively, and the preterm infants were 135.92 ± 5.72 mEq / L and 5.80 ± 0.70 mEq / L respectively, with no significant difference between the two groups P> 0.05). Compared with adults, neonatal hyponatremia than potassium and potassium higher than adults. Neonatal serum aldosterone levels of about 9 to 10 times the adult. Neonatal low serum sodium and high potassium is not due to lack of secretion of aldosterone.