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目的探讨广州市恙虫病发病的危险因素,为恙虫病防控提供依据。方法采用1∶1匹配的病例对照研究,以年龄和性别为匹配条件,分别选取202个病例和202例对照,运用统一设计的调查问卷,使用SPSS20.0进行单因素和多因素Logistic回归分析。结果单因素分析显示:外出或旅游史、高户外活动频次、住房类型和住宅附近有草地、菜地或沟塘在病例组和对照组间差异均有统计学意义(均有P<0.05)。多因素Logistic回归分析显示:外出或旅游史、高户外活动频次、住宅附近有草地、菜地或沟塘在病例组和对照组间差异均有统计学意义(均有P<0.05),其OR(95%CI)值分别是10.124(95%CI:2.220~46.163)、2.348(95%CI:1.431~3.853)和1.801(95%CI:1.180~2.748)。结论外出或旅游、高户外活动频次和住宅附近有草地、菜地或沟塘是广州市恙虫病发病的危险因素。
Objective To investigate the risk factors of tsutsugamushi disease in Guangzhou and provide evidence for the prevention and control of tsutsugamushi disease. Methods A case-control study of 1: 1 matching was conducted. Twenty-two cases and 202 controls were selected according to the age and gender. A questionnaire of uniform design was used and single-factor and multivariate Logistic regression analysis was performed using SPSS 20.0. Results Univariate analysis showed that there was significant difference between the case group and the control group in the time of going out or traveling, the frequency of outdoor activities, the type of housing and the grassland, vegetable field or ditch pond near the residence (all P <0.05). Multivariate Logistic regression analysis showed that there was significant difference between the case group and the control group (P <0.05), such as going out or traveling history, high frequency of outdoor activities, (95% CI: 2.220 to 46.163), 2.348 (95% CI: 1.431 to 3.853) and 1.801 (95% CI: 1.180 to 2.748), respectively. Conclusion The frequency of out-going or traveling, high-level outdoor activities and grassland, vegetable field or ditch pond near residential area are the risk factors of tsutsugamushi disease in Guangzhou.