论文部分内容阅读
目的:探讨45岁以下冠心病患者介入治疗围手术期的用药效果。方法:选择72例45岁以下的冠心病患者,将其分为治疗组和对照组,平均每组36例,在介入治疗的围手术期,两组均使用阿司匹林300mg/日,以及强化他汀类药物。治疗组在介入治疗术前每日应用氯吡格雷150mg,手术当日服600mg/日;对照组手术当日开始服用氯吡格雷,手术当日服300mg,其后服75mg/日。结果:治疗组冠心病症状控制效果明显优于对照组;不良反应人数明显少于对照组;复发率明显低于对照组。结论:在45岁以下冠心病患者进行介入治疗的围手术期,应用较大剂量氯吡格雷,其临床效果非常明显。
Objective: To investigate the perioperative effect of interventional therapy in patients with coronary heart disease under 45 years of age. Methods: Seventy-two patients with coronary heart disease under 45 years old were selected and divided into treatment group and control group with an average of 36 cases per group. In the perioperative period of interventional therapy, aspirin 300 mg / day was used in both groups and intensive statins drug. The patients in the treatment group were given clopidogrel 150 mg daily before operation and 600 mg daily on the operation day. The control group received clopidogrel on the day of operation, 300 mg on the day of operation and 75 mg / day thereafter. Results: The therapeutic effect of coronary heart disease in the treatment group was better than that of the control group. The number of adverse reactions was significantly less than that of the control group. The recurrence rate was significantly lower than that of the control group. Conclusion: In the perioperative period of interventional therapy for patients with coronary heart disease under 45 years of age, the clinical effect of clopidogrel is higher with larger doses.