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为探讨一氧化氮 (NO)在肝硬化患者血清中水平与肝功能及并发症的关系。采用硝酸还原酶法测定 35例肝硬化患者和 2 7例正常对照者血清中NO含量及 14例感染性和 11例非感染性腹水中NO含量。结果肝硬化组NO水平较正常对照显著升高 (P <0 0 0 1) ,NO水平随着肝功能Child -Pugh分级增加而升高。且血清白蛋白 <35g/L组的NO含量明显高于≥ 35g/L组 (P <0 0 5 )。说明NO与门脉高压并发症的形成及肝储备功能减退有关
To investigate the relationship between the serum level of nitric oxide (NO) in patients with liver cirrhosis and liver function and complications. Nitric acid reductase was used to determine the serum NO content in 35 cirrhotic patients and 27 normal controls and the NO content in 14 infective and 11 non-infectious ascites. Results The level of NO in cirrhosis group was significantly higher than that in control group (P <0.01). The level of NO increased with the increase of Child-Pugh classification. The NO content of serum albumin <35g / L group was significantly higher than that of ≥ 35g / L group (P <0 05). Description NO and the formation of portal hypertension complications and liver reserve dysfunction