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[目的]了解狂犬病疫苗的免疫效果及其影响因素,为预防狂犬病提供依据。[方法]选择姜堰市2009年内狂犬病疫苗接种者1948人,采用酶联免疫吸附试验(ELISA)检测狂犬病毒中和抗体,进行抗体阳性率分析。[结果]接种疫苗后抗体阳性率为95.12%,性别、季节和疫苗种类对抗体阳性率无明显影响,而不同年龄、免疫程序两者对抗体阳性率有影响。[结论]疫苗接种后抗体阳性率并非100%,必须进行狂犬抗体的检测,阴性人群必须加强免疫,以确保抗体的产生。
[Objective] To understand the immune effect of rabies vaccine and its influencing factors and provide evidence for preventing rabies. [Method] A total of 1948 rabies vaccine vaccinated persons were selected in Jiangyan in 2009. The neutralizing antibody of rabies virus was detected by enzyme - linked immunosorbent assay (ELISA), and the antibody positive rate was analyzed. [Result] The positive rate of antibody after vaccination was 95.12%. The sex, season and vaccine type had no significant effect on the positive rate of antibody, but different age and immune procedure had positive effect on antibody positive rate. [Conclusion] The positive rate of antibody after vaccination is not 100%, and the rabies antibody must be tested. The negative population must strengthen the immunity so as to ensure the antibody production.