葡萄糖注射液(下称糖液)按中国药典1985年版规定应作5-羟甲基糠醛(5-HMF)的限度测定。制剂生产中常因各种原因致使糖液中5—HMF含量超过限度。为保证制剂质量和用药安全,减少浪费,我们探讨了活性炭对糖液中5—HMF的吸附作用,并考查了影响其吸附的因素—温度、pH、活性炭的用量等,从而提出了采用活性炭吸附糖液中5—HMF的操作流程。 Glucose injection (hereinafter referred to as sugar) according to Chinese Pharmacopoeia 1985 edition should be made of 5-hydroxymethyl furfural (5-HMF) limit of determination. Formulation often due to various reasons, resulting in 5-HMF sugar content exceeds the limit. In order to ensure the preparation quality and medication safety and reduce the waste, we discussed the adsorption of 5-HMF in the sugar solution by activated carbon, and investigated the factors that affect its adsorption - temperature, pH, the amount of activated carbon, etc., thus proposed the use of activated carbon adsorption 5-HMF sugar in the operating flow.