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检测148例慢性肝病和肝癌患者血清中丙型肝炎病毒(hepatitisCvirus,HCV)核心区3种寡肽抗原(CP9,CP10,CP14)的抗体,结果显示其阳性率在慢性迁延型肝炎、慢性活动型肝炎、肝炎肝硬化和原发性肝癌患者中分别为7.7%,23.1%,23.5%和16.3%。在抗体阳性者中80%以上有乙型肝炎病毒(hepatitlsBvirus,HBV)感染证据,提示我国HBV和HCV重叠感染较为常见。在原发性肝癌中有HBV感染指标者95.9%,仅有HLV感染指标者占4.1%,说明迄今HBV仍是我国原发性肝癌的主要病毒学病因。
The antibodies against three kinds of oligopeptide antigens (CP9, CP10, CP14) in the core of hepatitis C virus (HCV) were detected in 148 patients with chronic liver disease and hepatocellular carcinoma. The results showed that the positive rates of these three antibodies in chronic persistent hepatitis and chronic active type Hepatitis, cirrhosis and primary liver cancer were 7.7%, 23.1%, 23.5% and 16.3%, respectively. More than 80% of the antibody positive patients have evidence of hepatitis B virus (HBV) infection, suggesting that HBV and HCV overlap infection is more common in our country. In primary hepatocellular carcinoma there are 95.9% of HBV infection indicators, only HLV infection indicators accounted for 4.1%, indicating that so far HBV is still the major virological cause of primary liver cancer in our country.