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目的研究不同几何构型颈内动脉中的血流动力学因素,分析其构型和动脉狭窄的关系,为颈内动脉狭窄的风险预测和早期诊断提供一定的血流动力学基础。方法对两种常见形状的颈内动脉——U形和V形在定常流条件下的流场分别进行数值模拟和粒子成像测速的实验研究。结果在其中较上游的弯曲处,血流动力学因素与弯曲曲率存在单调的相关关系,V形在此处的狭窄风险小于U形。但是在下游的弯曲处,由于两个弯曲的叠加效应,其血流动力学因素与此处的曲率不存在单调的相关关系。结论弯曲动脉的曲率和动脉狭窄的风险成正相关关系。但是在连续多个弯曲的动脉中,则需考虑弯曲的叠加效应。对此叠加效应的研究有助于解释多弯血管内狭窄多发的原因。
Objective To study the hemodynamic factors in different types of internal carotid arteries and to analyze the relationship between their configurations and arterial stenosis, so as to provide some hemodynamic basis for the risk prediction and early diagnosis of internal carotid artery stenosis. Methods Two common shapes of internal carotid arteries, U-shaped and V-shaped, were numerically simulated and measured by particle imaging. Results There was a monotonous correlation between hemodynamic factors and curvature of curvature at the more upstream bends, and the V-shaped stenosis here was less risky than the U-shape. However, at the downstream bend, there is no monotonous correlation between hemodynamic factors and curvature at this point due to the superposition of the two curves. Conclusions The curvature of curved artery has a positive correlation with the risk of arterial stenosis. However, in continuous multiple curved arteries, the superposition effect of bending needs to be considered. The study of this additive effect will help explain the multiple causes of stenosis in many curved vessels.