动态心电图监测是评价抗室性心律失常药物的有效手段。评价抗室性早博药物疗效的主要困难是如何排除室性早搏本身的自然变异以确定室性早搏的增加或减少确为药物所致。Kennedy等已发现随着动态心电图监测时间的延长,室性早搏能得到更全面的显示。Winkle等亦提出室性早搏的自然变异对药物疗效的准确评价影响重大。因而,从1978年起,Morganroth等先后在各种心脏病患者观察室性早搏的自然 Holter monitoring is an effective measure to evaluate anti-ventricular arrhythmia drugs. The main difficulty in evaluating the efficacy of antiarrhythmic drugs is how to rule out the natural variation of premature ventricular contractions to determine whether the increase or decrease of premature ventricular contractions is indeed caused by drugs. Kennedy et al. Have found that ventricular premature beats can be more fully displayed as the duration of the Holter monitoring increases. Winkle et al also proposed that the natural variation of premature ventricular contractions has a significant impact on the accurate evaluation of drug efficacy. Thus, since 1978, Morganroth, etc. have been observed in a variety of heart disease ventricular premature beats naturally