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目的探讨右美托咪定药理学特点及其临床应用新进展。方法通过临床应用右美托咪定药物,观察其药理学特点。结果右美托咪定是一种新型高选择性α2肾上腺素受体激动剂,具有镇静、镇痛、抗焦虑、抗交感、降低应激反应、稳定血流动力学等特点,同时对呼吸系统的影响轻微,具有其他镇静药无法比拟的效应。结论右美托咪定与其他镇静镇痛药物联合使用时有良好的协同效应,能明显减少其他镇静镇痛药的使用量,在重症监护(ICU)及麻醉科等领域具有良好的应用前景,深得临床医师的青睐。
Objective To investigate the pharmacological characteristics of dexmedetomidine and its new clinical application. Methods The clinical application of dexmedetomidine drugs to observe the pharmacological characteristics. Results Dexmedetomidine is a new and highly selective α2-adrenoceptor agonist with sedative, analgesic, anti-anxiety, anti-sympathetic, anti-stress response, stable hemodynamics and other characteristics of the respiratory system The effect is mild with unmatched effects of other sedatives. Conclusion Dexmedetomidine combined with other sedative analgesics has a good synergistic effect, can significantly reduce the amount of other sedative and analgesic drugs, and has good application prospect in the fields of intensive care (ICU) and anesthesiology. Won the clinician’s favor.