病人从甲状腺机能减退发展到甲状腺机能亢进是不常见的,只有少数病例报告有此病程变化。尽管其发病机理尚无明确的解释,但血清中与甲状腺功能相关的免疫球蛋白的变化可能是重要因素。 It is uncommon for patients to develop from hypothyroidism to hyperthyroidism, with only a few cases reporting this course of disease. Although there is no clear explanation for its pathogenesis, changes in serum thyroid-related immunoglobulins may be an important factor.