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人类嘌呤代谢异常,尿酸(UA)生成过多和/或排泄减少,使血中UA浓度增高称高尿酸血症。它是痛风的重要生化基础。长期高尿酸血症可引起痛风,是痛风的临床诊断条件之一。部分高尿酸血症可多年无痛风症状,如无关节炎、痛风石或与尿酸盐有关的肾结石,故亦被称为无症状性高尿酸血症。约10％～20％高尿酸血症发展成痛风。高尿酸血症的发生率约5％。其范围为2％～18％,但随着我国人民生活水平的提高及寿命延长,其发生率正迅速增加。高尿酸血症不是痛风的代名词,但无症状性高尿酸血症则被认为是痛风发生的
Abnormal human metabolism of purine, uric acid (UA) generation and / or reduced excretion, so that the blood UA concentration increased hyperuricemia. It is an important biochemical basis of gout. Long-term hyperuricemia can cause gout, gout is one of the clinical diagnostic conditions. Some hyperuricemia can be years free of gout symptoms, such as no arthritis, tophi or urate-related kidney stones, it is also known as asymptomatic hyperuricemia. About 10% to 20% of hyperuricemia develop into gout. The incidence of hyperuricemia is about 5%. It ranges from 2% to 18%, but its incidence is rapidly increasing with the improvement of living standards and life expectancy of our people. Hyperuricemia is not synonymous with gout, but asymptomatic hyperuricemia is considered gout.