论文部分内容阅读
目的:观察采用左卡尼汀注射液联合血液透析对慢性肾功能衰竭患者进行治疗的临床效果。方法:选取50例2014年2月至2016年2月于翁源县人民医院就诊治疗慢性肾功能衰竭患者,随机均分为治疗组与对照组各25例。两组均于常规对症治疗下给予血液透析治疗,对照组每周血透治疗3次,治疗组每周血透治疗2次,每次透析完给予患者左卡尼汀静脉注射治疗。分析比较两组治疗效果,不良反应发生情况及治疗前后各项生化指标改善情况。结果:治疗组治疗总有效率92.00%明显高于对照组的治疗总有效率68.00%,组间比较,差异具有统计学意义(P<0.05);两组治疗后Scr、Ccr、BUN比较,治疗组改善情况均明显优于对照组,组间比较,差异具有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:左卡尼汀注射液联合血液透析治疗慢性肾功能衰竭,临床效果佳,可明显改善患者临床症状,改善肾功能。
Objective: To observe the clinical effect of levocarnitine injection combined with hemodialysis on patients with chronic renal failure. Methods: Fifty patients with chronic renal failure who were treated in Wengyuan People’s Hospital from February 2014 to February 2016 were randomly divided into treatment group (25 cases) and control group (25 cases). Patients in both groups were given hemodialysis treatment under conventional symptomatic treatment, hematopoietic treatment in control group 3 times a week, and hemodialysis treatment group 2 times per week. Each time hemodialysis was given, patients were given L-carnitine intravenously. Analysis and comparison of the two groups treatment effect, adverse reactions and the improvement of various biochemical indicators before and after treatment. Results: The total effective rate of the treatment group was 92.00%, which was significantly higher than that of the control group (68.00%). The differences between the two groups were statistically significant (P <0.05) (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion: L-carnitine injection and hemodialysis in the treatment of chronic renal failure, clinical effect is good, can significantly improve the clinical symptoms and improve renal function.