药物是防治疾病的物质,可影响机体的生化生理功能,产生药理效应。药物在机体各种酶系统的影响下引起生物转化,最后排出体外。药物代谢酶简称药酶,常分为微粒体酶系和非微粒体酶系两大类。前者主要存在于肝脏,后者除肝脏外也存在于血浆及其他组织中。这二类酶系中,每一类又可分为:水解酶类、氧化还原酶类和共轭结合酶类等。 Drugs are substances that prevent and cure diseases and can affect the body’s biochemical and physiological functions, resulting in pharmacological effects. Drugs in the body under the influence of various enzyme systems cause biological transformation, and finally excreted. Drug metabolism enzyme referred to as enzyme, often divided into microsomal enzymes and non-microsomal enzymes in two categories. The former mainly in the liver, the latter in addition to the liver also exists in plasma and other tissues. These two types of enzymes, each category can be divided into: hydrolytic enzymes, oxidoreductases and conjugate enzymes.