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目的:对比分析二甲双胍与马来酸罗格列酮片对2型糖尿病的临床疗效。方法:选择大庆油田总医院2012年1月-2014年12月初诊2型糖尿病患者60例,随机分为对照组和观察组。疗程4周,以餐后7个时间点血糖值、游离脂肪酸为检测指标。结果:疗后两组各时间点血糖值均明显下降,且观察组优于对照组,差异具有统计学意义(P<0.05)。结论:二甲双胍马来酸罗格列酮片和二甲双胍均有一定控制血糖的作用,且前者效果更佳。
Objective: To compare and analyze the clinical effect of metformin and rosiglitazone maleate on type 2 diabetes mellitus. Methods: Sixty newly diagnosed type 2 diabetic patients in Daqing Oilfield General Hospital from January 2012 to December 2014 were randomly divided into control group and observation group. Treatment for 4 weeks, 7 points after meal blood glucose, free fatty acids as a test indicator. Results: After treatment, the blood glucose of the two groups were significantly decreased at each time point, and the observation group was better than the control group, the difference was statistically significant (P <0.05). Conclusion: Metformin maleate rosiglitazone tablets and metformin have a certain effect of controlling blood sugar, and the former effect is better.