目的探讨米非司酮在绝经后妇女取宫内节育器(IUD)术前的应用价值。方法选择我院门诊绝经后取IUD妇女160例,分为观察组与对照组,每组80例。观察组在取IUD术前2d口服米非司酮75mg,每天1次,第3天行取IUD术。对照组不服药直接手术操作取IUD。比较两组宫颈软化效果、手术时间、术中出血量、疼痛程度及一次取IUD成功率。结果观察组宫颈软化好,手术时间短,术中出血少,疼痛程度轻;观察组一次取IUD成功率高于对照组(98.6%vs.57.5%)(P<0.05)。观察组服米非司酮未出现明显不良反应。结论绝经后妇女取IUD术前应用米非司酮利于宫颈软化与扩张,取IUD成功率高,痛苦小,值得临床推广。 Objective To investigate the value of mifepristone in preoperative menopausal women with intrauterine device (IUD). Methods 160 cases of IUD women were selected after outpatient menopause in our hospital, divided into observation group and control group with 80 cases in each group. The observation group received oral mifepristone 75mg twice daily before IUD operation, and IUD was performed on the third day. The control group did not take the direct surgical operation to take IUD. Cervical softening effect, operation time, intraoperative blood loss, pain level and IUD success rate were compared between the two groups. Results The observation group had good cervical softening, shorter operative time, less intraoperative bleeding and less pain. The success rate of IUD in the observation group was higher than that of the control group (98.6% vs.57.5%, P <0.05). Observation group taking mifepristone no obvious adverse reactions. Conclusion Postmenopausal women taking IUD preoperative application of mifepristone in cervical softening and expansion, take IUD high success rate, little pain, is worth clinical promotion.