儿童血浆胆固醇较低,没有动脉粥样硬化的临床表现。但动脉壁脂肪斑纹在胎儿期开始形成,如果母亲怀孕期间高胆固醇,会增加胎儿脂肪斑纹形成。在FELIC研究中证明动脉粥样硬化损害发生在儿童时期。研究对象为156例儿童,年龄1～13岁,根据母亲怀孕期间胆固醇是否正常,将儿童随机分为 Children with lower plasma cholesterol, no clinical manifestations of atherosclerosis. But the arterial wall fat markings begin to form in the fetus, if the mother during pregnancy, high cholesterol, will increase fetal fat markings formation. In the FELIC study, evidence of atherosclerotic lesions occurred in childhood. The study was performed on 156 children aged 1 to 13 years. According to whether the mother’s cholesterol was normal during pregnancy, children were randomly divided into