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近年来,胃高级别上皮内瘤变作为一个病理诊断已越来越多地应用于临床。实际上,这一概念应用之前曾经历了一系列的演变,其范畴逐步完善,但目前东西方专家对这一概念的理解却有较大的分歧,而临床医生和病理科医生也经常就这一术语争论不休。临床医生对胃上皮内瘤变的处理感到很困惑,到底选择内镜黏膜下剥离术(ESD)、腔镜治疗还是开放手术,目前尚无统一标准。外科医生和病理科医生的良好沟通,可能是目前处理上皮内瘤变的最佳方式;而癌前病变的研究和外科治疗,可能是今后肿瘤外科治疗的方向之一。
In recent years, high-grade gastric intraepithelial neoplasia as a pathological diagnosis has been increasingly used in clinical. In fact, this concept has undergone a series of evolutions before its application, and its category has been gradually improved. However, there is a great divergence in the understanding of this concept by the East-West experts at present, and clinicians and pathologists often do this A term endless debate. Clinicians are puzzled by the treatment of intraepithelial neoplasia. In the end, there is no uniform standard for endoscopic submucosal dissection (ESD), endoscopic treatment or open surgery. Surgeons and pathologists good communication may be the best way to deal with intraepithelial neoplasia; and precancerous lesions research and surgical treatment may be one of the future direction of surgical treatment of tumors.