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目的分析山东省1990-2007年乙型肝炎发病的流行趋势,发现重点人群,进一步探讨防治策略。方法根据历年乙肝报告的发病资料和人口资料,计算历年发病率以及性别、年龄别发病率,并建立简单线性回归模型进行统计分析。结果1990-2007年山东省共报告乙肝发病437 094例,年均发病率27.32/10万,男性发病率(38.42/10万)高于女性(15.83/10万);总体发病率呈上升趋势,但0～9岁年龄组呈显著下降趋势;平均发病年龄呈后移趋势。结论男性青壮年为乙肝发病的重点人群,预防乙肝应在提高对新生儿乙肝疫苗接种率的基础上,加强对其他人群尤其是高危人群的接种工作。
Objective To analyze the prevalence of hepatitis B in Shandong Province from 1990 to 2007 and find out the key population and to further explore the prevention and treatment strategies. Methods Based on the reported incidence and population data of hepatitis B in the past years, the incidence of the disease and the incidence of gender and age were calculated, and a simple linear regression model was established for statistical analysis. Results A total of 437 094 cases of hepatitis B were reported in Shandong Province from 1990 to 2007. The average annual incidence rate was 27.32 / 100 000. The incidence of males was higher than that of females (38.42 / 100 000) (15.83 / 100 000). The overall incidence was on the rise, However, the 0 ~ 9 age group showed a significant downward trend; the average age of onset showed a backward trend. Conclusions Male young adults are the key population of hepatitis B. The prevention of hepatitis B should increase the vaccination rate of newborn hepatitis B and strengthen the vaccination of other people especially those at high risk.