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目的探讨不孕症妇女自然周期中尿黄体生成素(LH)半定量试纸动态检测内源性LH峰值的应用。方法采用尿LH半定量试纸结合阴道超声,观察不孕症妇女排卵时间、排卵率、早发LH峰、未破裂黄素化卵泡(LUF)的发生率以及尿LH半定量检测试纸预测排卵的准确性。结果 102例不孕症妇女244个自然周期的卵泡发育中,尿LH半定量试纸测定结果为尿LH阳性率56.56%,阴性率18.03%,早发LH峰发生率25.41%。根据尿LH峰测定结果分为阳性组、阴性组及早发LH峰组,排卵率分别为91.30%、63.64%和54.84%,LUF发生率分别为8.70%、31.82%和41.94%。3组排卵率比较,LH阳性组高于其他两组(P<0.05),3组LUF率比较阳性组低于其他两组(P<0.05)。结论在自然周期中利用尿LH半定量试纸动态检测内源性LH峰值,有利于判断卵泡发育情况,具有一定的应用价值。
Objective To investigate the application of semi-quantitative test strip of urine LH (natural LH) in spontaneous women during spontaneous cycles to detect endogenous LH peak. Methods Urine LH semi-quantitative test paper combined with vaginal ultrasound was used to observe the ovulation time, ovulation rate, early onset LH peak, unruptured luteinizing follicle (LUF) incidence rate and urine LH semi-quantitative test strips to predict ovulation accuracy. Results In 244 spontaneous follicles of 244 infertile women, urinary LH semi-quantitative test paper was 56.56%, negative rate 18.03% and early peak LH rate 25.41%. According to the results of urine LH peak, the ovulation rate was 91.30%, 63.64% and 54.84% respectively. The incidence of LUF was 8.70%, 31.82% and 41.94% respectively. The ovulation rate in the three groups was higher than that in the other two groups (P <0.05). The LUF rate in the three groups was lower than that in the other two groups (P <0.05). Conclusions The dynamic detection of endogenous LH peak by urine semi-quantitative test strip in the natural cycle is helpful to judge the follicular development and has certain value.