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粒巨—细胞集落刺激因子(GM—CSF)在急性白血病中的应用已有报道,我们应用灵杆菌素(中外合资德阳华康药业有限公司产品)对恶性肿瘤化疗后白细胞减少症患者进行了观察。并与GMCSF进行了对比研究。现报道如下。 1 临床资料 1.1 病例选择:我们自1996年1月至1998年9月共收治恶性肿瘤患者280例,其中94例患者于化疗后出现白细胞减少,分别为急性白血病16例,肺癌23例,大肠癌25例,恶性淋巴瘤20例,乳腺癌10例。本组患者94例作为研究组。男66例,女28例;年龄22～63岁,平均年龄42.5岁。
The application of granulocyte giant cell colony stimulating factor (GM-CSF) in acute leukemia has been reported. We applied leucocintine (a product of the Sino-foreign joint venture Deyang Huakang Pharmaceutical Co., Ltd.) to treat leukopenia after chemotherapy for malignant tumors. Observed. And compared with GMCSF. The report is as follows. 1 Clinical data 1.1 Case selection: We have treated 280 patients with malignant tumors from January 1996 to September 1998. Of these, 94 patients had leukopenia after chemotherapy, including 16 acute leukemias, 23 lung cancers, and large intestine cancers. In 25 cases, there were 20 cases of malignant lymphoma and 10 cases of breast cancer. 94 patients in this group as a study group. 66 males and 28 females; aged 22-63 years, mean age 42.5 years.