A large number of unconventional investigations have been implemented, tested, and validated in the field of microgeophysics, with the aim being to solve specific diagnostic and/or monitoring problems regarding civil engineering and cultural heritage studies. The investigations were carried out using different tomographic 2D and 3D approaches as well as different energy sources, namely sonic, ultrasonic and electromagnetic (radar) waves, electric potential fields, and infrared thermography. Many efforts have been made to modify instruments and procedures in order to improve the resolution of the surveys as well as to greatly reduce the time of the measurements without any loss of information. The main new methodologies here discussed are the sonic imprint, the global tomographic traveltime, the electrical resistivity tomography, and the control of external films (patinas) grown on stone monuments. The results seem to be very promising and suggest that it is the moment to dedicate time and effort to this new branch of geophysics, so that these methodologies can be used even more to diagnose, monitor, and safeguard not only engineering buildings and large structures but also ancient monuments and cultural artifacts, like pottery, statues, etc.. A large number of unconventional investigations have been implemented, tested, and validated in the field of microgeophysics, with the aim being to solve specific diagnostic and / or monitoring problems concerning civil engineering and cultural heritage studies. The investigations were carried out using different tomographic 2D and 3D Methods as well as different energy sources, namely sonic, ultrasonic and electromagnetic (radar) waves, electric potential fields, and infrared thermography. Many efforts have been made to modify instruments and procedures in order to improve the resolution of the surveys as well The main new methodologies here about are the sonic imprint, the global tomographic traveltime, the electrical tomography traveltime, the electrical resistivity tomography, and the control of external films (patinas) grown on stone monuments. The results seem to be very promising and suggest that it is the moment to dedicate time and effort to this new branch of geophysics, so that these methodologies can be used even more to diagnose, monitor, and safeguard not only engineering buildings and large structures but also ancient monuments and cultural artifacts, like pottery, statues, etc ..