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目的分析首次热性惊厥(FC)患儿212例的复发情况及可能引起的复发的11种相关因素,进行有效的防治措施,从而减少FC的复发。方法随机选择212例首次发作的热性惊厥患儿,对他们随访2～4年进行总结,对影响复发的11种因素进行多元回归分析。结果首次热性惊厥复发率是59.6%,且与发病时体温、年龄成负相关;与家族史、反复上呼吸道感染、营养不良呈正相关;与性别、围产期、佝偻病、贫血、喂养方式无关。结论由于FC可造成惊厥性脑损伤,减少或控制FC的复发,可从预防或治疗引起FC复发的上述5种因素着手,减轻或防止患儿智能损伤。
Objective To analyze the relapse of 212 patients with first febrile seizures (FC) and 11 related factors that may cause recurrence, and to provide effective prevention and treatment measures to reduce the recurrence of FC. Methods A total of 212 children with first seizure of febrile seizures were randomly selected and followed up for 2-4 years. Multivariate regression analysis was performed on 11 factors that affected relapse. Results The recurrence rate of the first febrile seizures was 59.6%, and was negatively correlated with body temperature and age at onset. It was positively correlated with family history, recurrent upper respiratory tract infection and malnutrition. It had no correlation with gender, perinatal, rickets, anemia and feeding patterns . Conclusion Because FC can cause convulsive brain injury and reduce or control the recurrence of FC, we can start from the prevention or treatment of the above five factors that cause FC recurrence to reduce or prevent the intelligent injury in children.