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目的 :探讨某市自来水有机提取物对小鼠的诱变性。方法 :采集淮河水源水、自来水厂滤池出水、氯化消毒自来水及大型贮水箱水各 2 0 0L。经吸附 ,提取有机物后予小鼠灌胃染毒 ,检测胸骨骨髓嗜多染红细胞微核率和精子畸形率 ,并作U检验。结果 :淮河水源水及氯化消毒的自来水均有一定的致突变性。毒性大小依次为氯化消毒的自来水 >贮水箱水 >水源水 >滤池出水。结论 :淮河水源水已受到有机诱变物的污染 ,混凝沉淀具有去除有机物、降低源水诱变性作用 ,而氯化消毒使水质的诱变性增高。
Objective: To investigate the mutagenicity of organic extracts of tap water in a city on mice. Methods: The Huai River source water, water filter plant effluent, chlorinated disinfection of tap water and large storage tank water 200L. After adsorption and extraction of organic compounds, the mice were gavaged with virus and the micronucleus rate and sperm deformity rate of bone marrow erythrocytes were detected. Results: The Huai River water and chlorinated disinfection of tap water have a certain mutagenicity. Toxicity followed by chlorinated disinfection of tap water> storage tank water> water source> filter effluent. Conclusion: The water from the Huaihe River has been contaminated by organic mutagen. The coagulation and sedimentation have the functions of removing organic compounds and reducing the mutagenicity of the source water. Chlorination disinfection increases the mutagenicity of water quality.