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目的探讨急性重症胰腺炎(SAP)早期肠内营养(FEN)的疗效。方法将急性重症胰腺炎患者56例随机分为实验组和对照组,试验组早期行肠道内营养,对照组给予静脉营养至进食,分别观察血清白蛋白和淀粉酶水平、并发症、感染率、病死率、住院时间及费用。结果血清白蛋白均升高,组间差异有显著性(P<0.05),实验组血清白蛋白水平高于对照组,实验组在并发症发生率、感染率、住院时间和费用低于对照组(P<0.05),血淀粉酶水平、死亡率无明显差异(P>0.05)。结论急性重症胰腺炎患者早期行肠内营养能改善ASP患者的营养状况,降低并发症发生率、感染率,缩短病程,减少医疗费用。
Objective To investigate the efficacy of early enteral nutrition (FEN) in acute severe pancreatitis (SAP). Methods Fifty-six patients with severe acute pancreatitis were randomly divided into experimental group and control group. The experimental group received early enteral nutrition and the control group received intravenous nutrition. The levels of serum albumin and amylase, complications, infection rate, Fatality rate, length of hospital stay and costs. Results Serum albumin increased, with significant difference between groups (P <0.05). Serum albumin level in the experimental group was higher than that in the control group. The incidence of complications, infection rate, hospitalization time and cost in the experimental group were lower than those in the control group (P <0.05), serum amylase level and mortality had no significant difference (P> 0.05). Conclusion Early enteral nutrition in patients with acute severe pancreatitis can improve nutritional status of patients with ASP, reduce the incidence of complications, infection rate, shorten the course of disease, reduce medical costs.