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目的对239例HIV感染者基本情况、皮肤损害和血浆CD4+淋巴细胞计数关系进行分析,探讨HIV感染者并发皮肤病的特点。方法采用比较分析,分为A组有皮肤损害(112人),B组无皮肤损害(127人)。统计皮肤瘙痒及皮疹、黏膜溃疡、口腔糜烂、疱疹等五类皮肤损害,分析两组基本情况差异、血浆CD4+淋巴细胞计数差异及皮损组皮肤损害评分与血浆CD4+淋巴细胞计数的关系。结果 239例分析对象皮肤损害发生率为46.86%;皮肤损害组中有皮肤瘙痒者71.43%,皮疹43.75%,黏膜溃疡14.29%,口腔糜烂11.61%,疱疹10.71%;两组均在30～39岁年龄段发病率较高。皮损组血浆CD4+淋巴细胞计数明显低于无皮损组,差异有统计学意义。皮损组血浆CD4+淋巴细胞计数与皮损严重程度无相关性。结论在HIV感染并发皮肤损害者中,皮肤瘙痒和皮疹较为常见。血浆CD4+淋巴细胞计数下降至200个/mm3以下时容易发生皮肤损害,但皮损严重程度与血浆CD4+淋巴细胞计数无明显关系。
Objective To analyze the relationship between the basic situation of 239 cases of HIV infection, skin lesions and plasma CD4 + lymphocyte count to explore the characteristics of HIV-infected persons complicated with skin diseases. Methods By comparative analysis, divided into A group of skin lesions (112), B group without skin lesions (127). The incidence of pruritus and skin rash, mucosal ulcer, oral erosion and herpes were statistically analyzed. The differences of basic conditions, the difference of CD4 + lymphocyte count and the relationship between the skin lesion scores and CD4 + lymphocyte count were analyzed. Results The incidence of skin lesions in 239 subjects was 46.86%. Skin lesions were found in 71.43% of skin lesions, 43.75% of skin lesions, 14.29% of mucosal ulcers, 11.61% of oral erosion and 10.71% of herpes lesions in both groups. The higher the incidence of age. The number of CD4 + lymphocyte in the lesion group was significantly lower than that in the non-lesion group, the difference was statistically significant. There was no correlation between the plasma CD4 + lymphocyte count and the severity of skin lesions in the lesion group. Conclusions Skin pruritus and rashes are more common in people with HIV-associated skin lesions. Plasma CD4 + lymphocyte count down to 200 / mm3 following prone skin damage, but the severity of the lesion and plasma CD4 lymphocyte count no significant relationship.