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目的研究婴幼儿食物过敏的临床特征,为该病的诊治提供依据。方法以温州市区儿童消化科门诊就诊的0~36月儿童为研究对象。向家长询问病史并填写调查表,同时检测血清总IgE及牛奶、鸡蛋黄、鸡蛋清、大豆、海鱼、虾、螃蟹等7项特异性IgE(sIgE)。根据病史及sIgE检测结果定可疑病例,然后进行食物剔除试验并随访6月。结果本组食物过敏检出率为18.99%。最常见的过敏原为牛奶(55.56%)和鸡蛋清(15.56%)。本组患儿最常见临床表现为湿疹及便血。结论温州市区婴幼儿最常见的食物致敏原为牛奶和鸡蛋清,最常见临床表现为湿疹及便血,食物回避可有效治疗食物过敏。
Objective To study the clinical features of food allergy in infants and young children and provide the basis for the diagnosis and treatment of the disease. Methods Children from 0 to 36 months in outpatient department of children’s gastroenterology in Wenzhou city were studied. The parents were asked about their medical history and questionnaires. Seven serum IgE (sIgE) levels, including serum total IgE, milk, egg yellow, egg white, soybeans, marine fish, shrimp and crabs, were also detected. According to the history and sIgE test results were determined suspicious cases, and then food cull test and follow-up in June. Results The rate of food allergy in this group was 18.99%. The most common allergens were milk (55.56%) and egg white (15.56%). The most common clinical manifestations of children in this group of eczema and hematochezia. Conclusion The most common food allergens in infants and young children in Wenzhou are milk and egg white. The most common clinical manifestations are eczema and blood in the stool. Food avoidance can effectively treat food allergy.