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2型糖尿病发病中心环节是胰岛素抵抗和胰岛β细胞的功能缺陷。胰岛素抵抗贯穿在2型糖尿病的发生、发展的全过程。β细胞功能缺陷是发病必要条件。胰岛素抵抗常合并一系列心血管危险因素,如:高血糖,高血压,高血脂,肥胖,多种心血管危险因素“聚集”现象又称为“代谢综合征”。这
The pathogenesis of type 2 diabetes mellitus is insulin resistance and pancreatic β-cell dysfunction. Insulin resistance runs through the whole process of the development of type 2 diabetes. Beta cell dysfunction is a prerequisite for morbidity. Insulin resistance often associated with a series of cardiovascular risk factors, such as: high blood sugar, hypertension, hyperlipidemia, obesity, a variety of cardiovascular risk factors “aggregation” phenomenon, also known as “metabolic syndrome.” This