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目的 探讨治疗毒鼠强中毒的药物和方法。方法 按患者到院就诊时间的先后顺序将其分为丙成酸钠组、二巯基丙磺酸钠组和综合治疗组,3组均接受综合治疗。丙戊酸钠组在综合治疗的基础上加用丙戊酸钠持续1个月停药,二巯基丙磺酸钠组在综合治疗的基础上加用二巯基丙磺酸钠。持续1周后停药,然后根据临床观察指标进行统计。结果 经统计学处理,3组治疗结果没有显著性差异。结论 二巯基丙磺酸钠组治疗毒鼠强中毒无显著疗效,丙戊酸钠在防治远程抽搐方面有一定作用,应用镇静剂控制抽搐是治疗的关键,并进行综合治疗才能取得满意的效果。
Objective To explore the drugs and methods for the treatment of tetramine poisoning. Methods The patients were divided into sodium propionate group, sodium dimercaptopropane sulfonate group and comprehensive treatment group according to the order of patients visiting hospital, and the three groups received comprehensive treatment. Sodium valproate group on the basis of comprehensive treatment plus sodium valproate for 1 month withdrawal, sodium dimercaptopropanesulfonate group on the basis of comprehensive treatment with sodium dimercaptopropane sulfonate. After 1 week of withdrawal, statistics were made based on the clinical observation. The results of the statistical analysis, the three treatment results no significant difference. Conclusion Sodium dimercaptopropane sulfonate treatment of tetramine poisoning no significant effect, sodium valproate in the prevention and treatment of long-term effects of convulsions, the use of sedation control of convulsions is the key to treatment, and comprehensive treatment in order to obtain satisfactory results.