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目的:探讨宫血宁胶囊用于治疗宫内放置节育器后异常子宫出血的临床疗效。方法:350例宫内置器后异常出血患者随机分为观察组(175例)与对照组(175例),其中观察组给予宫血宁胶囊治疗,对照组给予抗菌止血常规西药治疗,比较两组患者治疗前后月经异常变化情况及治疗效果。结果:①观察组治愈率、总有效率分别为56.00%和92.57%,对照组治愈率、总有效率为25.71%和75.43%,组间差异有统计学意义(P<0.01)。②经过治疗,观察组与对照组患者月经异常症状均得到明显缓解,与治疗前比较差异有显著性(P<0.01),其中观察组患者经量增多、经期延长和经间点滴出血等症状例数分别减少至9例、7例和1例,对照组减少至34例、30例和15例,组间差异有统计学意义(P<0.05)。③经过治疗,观察组患者平均月经持续时间从11.74±4.69d减少至6.92±2.34d,对照组从12.11±5.25d减少至9.28±3.14d,两组间差异有统计学意义(P<0.05)。结论:宫血宁胶囊可有效治疗因宫内放置节育器所引起的子宫异常出血,且疗效优于抗菌止血西药治疗,值得进一步推广。
Objective: To investigate the clinical effect of Gongxuening Capsule in the treatment of abnormal uterine bleeding after intrauterine placement of IUD. Methods: One hundred and fifty-five cases of abnormal bleeding after intrauterine device implantation were randomly divided into observation group (175 cases) and control group (175 cases), in which observation group was treated with Gongxuening capsule, while control group was given anti-bacterial and hemostatic conventional western medicine. Patients before and after treatment of abnormal menstruation and treatment. Results: ① The cure rate and total effective rate of the observation group were 56.00% and 92.57% respectively. The cure rate and the total effective rate of the control group were 25.71% and 75.43%, respectively. There was significant difference between the two groups (P <0.01). ② After treatment, the symptoms of menstruation in observation group and control group were significantly relieved, with significant difference (P <0.01) before treatment, in which the symptoms such as increased volume, prolonged menstrual period and bleeding during operation The number decreased to 9 cases, 7 cases and 1 case, while the control group reduced to 34 cases, 30 cases and 15 cases, the difference was statistically significant (P <0.05). ③ After treatment, the mean duration of menstruation in observation group decreased from 11.74 ± 4.69d to 6.92 ± 2.34d, while in control group decreased from 12.11 ± 5.25d to 9.28 ± 3.14d, the difference was statistically significant (P <0.05) . Conclusion: Gongxuening Capsule can effectively treat abnormal uterine bleeding caused by intrauterine placement of IUD, and its efficacy is superior to that of antibacterial and hemostatic western medicine. It is worth further promotion.