论文部分内容阅读
目的观察CIK(Cytokine-Induced Killer,CIK)细胞治疗恶性胸腔积液临床效果。方法将2010年7月-2011年9月到本院进行恶性胸腔积液治疗的92例病患随机分成两组各46例,治疗组采取CIK细胞、顺铂以胸腔内部的灌注的方式进行治疗,对照组采取顺铂以胸腔内部的灌注的方式进行治疗,对比治疗前后有效率、两组生存质量评分、发热以及不良反应。结果治疗组有效率和生存质量评分均高于对照组(P<0.05),且不良反应也少于对照组。结论应用CIK细胞治疗恶性胸腔积液进行治疗,安全有效,有极大的研究和推广价值。
Objective To observe the clinical effect of CIK (Cytokine-Induced Killer, CIK) cells in the treatment of malignant pleural effusion. Methods 92 patients with malignant pleural effusion who were admitted to our hospital from July 2010 to September 2011 were randomly divided into two groups (n = 46). CIK cells were used in the treatment group. Cisplatin was administered intrathoracially The control group was treated with cisplatin by intrathoracic perfusion, comparing the effective rate before and after treatment, quality of life score, fever and adverse reactions in both groups. Results The effective rate and quality of life in the treatment group were higher than those in the control group (P <0.05), and the adverse reactions were also less than those in the control group. Conclusion CIK cells for the treatment of malignant pleural effusion, safe and effective, have great research and promotion value.