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早在1942年即有学者开始注意到严重应激事件可以导致死亡,20世纪90年代,首先由日本学者报道在绝经期妇女因严重的情感应激而发生可逆性心肌病,从而使应激性心肌病得到广泛重视[1]。在ICU中,患者多存在严重疾病,精神及躯体均处于不同程度的应激状态,使得中枢神经系统以及自主神经系统功能发生改变或受损,多表现为交感神经过度兴奋、内源性儿茶酚胺过度刺激心肌细胞(或称交感风暴),从而对心血管
As early as 1942, scholars began to notice that serious stressful events could lead to death. In the 1990s, firstly, Japanese scholars first reported that reversible cardiomyopathy occurs in menopausal women due to severe emotional stress, so that stress Cardiomyopathy has received widespread attention [1]. In the ICU, there are many patients with severe diseases, the spirit and the body are at different levels of stress, making the central nervous system and autonomic nervous system function change or damage, more performance of sympathetic over-excited, excessive endogenous catecholamines Stimulate cardiomyocytes (or sympathetic storm) and thus cardiovascular