论文部分内容阅读
目的探究锌制剂联合布拉酵母菌散治疗小儿迁延性腹泻的临床效果。方法选取彭泽县人民医院儿科2013年5—12月收治的迁延性腹泻患儿80例,将患儿随机分为观察组和对照组,各40例。对照组进行促消化、纠正水电解质等常规治疗,同时给予布拉酵母菌散,观察组在对照组的基础上联合葡萄糖酸锌治疗。比较两组患者的治疗效果及细胞免疫指数。结果观察组患儿总有效率(95.0%)高于对照组(77.5%),差异有统计学意义(P<0.05)。两组患儿治疗前CD+4、CD+8细胞分数及CD+4/CD+8细胞比值比较,差异无统计学意义(P>0.05);观察组患儿治疗后CD+4细胞分数、CD+4/CD+8细胞比值均高于对照组,CD+8细胞分数低于对照组,差异有统计学意义(P<0.05)。结论锌制剂联合布拉酵母菌散治疗小儿迁延性腹泻可以有效地改善患儿的营养情况,尽快达到止泻效果,提升患儿的自身免疫力。
Objective To investigate the clinical efficacy of zinc preparation combined with yeast broncho-altogenetic powder in the treatment of pediatric persistent diarrhea. Methods Eighty children with persistent diarrhea who were treated in Pengze County People’s Hospital from May to December in 2013 were randomly divided into observation group and control group, 40 cases in each group. The control group to promote digestion, water and electrolyte to correct conventional treatment, while giving Saccharomyces boulardi, the observation group in the control group based on the combination of zinc gluconate treatment. The therapeutic effect and cellular immune index of two groups were compared. Results The total effective rate (95.0%) in observation group was higher than that in control group (77.5%), the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the scores of CD + 4, CD + 8 cells and the ratio of CD + 4 / CD + 8 before treatment (P> 0.05). The scores of CD + 4 cells, The ratio of CD + 4 / CD + 8 cells was higher than that of the control group, and the score of CD + 8 cells was lower than that of the control group (P <0.05). Conclusion Zinc preparations combined with Bladderwort powder in children with persistent diarrhea can effectively improve the nutritional status of children with antidiarrheal effect as soon as possible to enhance children’s autoimmunity.