一例49岁的女病人,严重水样腹泻(每天2～4L),体重明显减轻,低血钾和低胃酸分泌。小肠灌注,证明有活性基部肠分泌。尽管进行了充分的临床实验研究,仍然不清楚其分泌性腹泻的原因。患者经消炎痛、泼尼松、三氟拉嗪等药物治疗,但无明显改善,病程恶化达40多天。试验口服碳酸锂(300mg,每天2次)后48小时内,粪量从每天2L 减至0.5L,第4天腹 A 49-year-old female patient has severe watery diarrhea (2-4L daily), significant weight loss, hypokalemia and hypo-gastric acid secretion. Small intestine perfusion, proves active intestinal secretion. Despite adequate clinical laboratory studies, the cause of its secretory diarrhea remains unclear. Patients with indomethacin, prednisone, trifluoperazine and other drugs, but no significant improvement in the course of deterioration of more than 40 days. After 48 hours of oral administration of lithium carbonate (300 mg twice daily), the fecal volume was reduced from 2 L to 0.5 L per day,