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确定韩国健康女性的年龄对体内锌代谢及其状态的影响。测定食用典型韩式饮食的青年和老年女性体内的锌含量,给予受试者口服和静注富含Zn~(65)和Zn~(70)的同位素标记物。采集受试对象的血样、24 h尿样和粪样。在青年女性中利用七隔模型法测定动态血清锌含量。运用Miller法测定快速交换性锌池(exchangeable zinc pool,EZP)。老年女性的血浆锌浓度显著高于青年女性(P<0.05)。老年女性的快速交换性锌池和尿锌也显著高于青年女性。部分及总锌吸收量和内源性粪代谢锌的丢失在青年和老年女性中无差异。与美国女性体内动态锌水平比较,韩国女性血浆锌量和快速交换性锌池的参数无显著差异,韩国女性吸收锌和锌进入体内组织的速率偏低。韩国妇女体内总锌含量低于美国妇女。
Determining the effect of age of healthy Korean women on zinc metabolism and their status in the body. The contents of zinc in young and old women consuming typical Korean diet were determined. Oral and intravenous injection of Zn ~ (65) and Zn ~ (70) -containing isotope markers were given to the subjects. Blood samples were collected from the subjects, 24 h urine samples and fecal samples. Dynamic seizures of zinc in young women using seven septum model. Determination of exchangeable zinc pool (EZP) by Miller method. Plasma zinc concentrations in elderly women were significantly higher than those in young women (P <0.05). Elderly women’s rapid exchange zinc pool and urine zinc were also significantly higher than young women. Partial and total zinc uptake and loss of endogenous dung metabolized zinc were not different among young and old women. Compared with the dynamic zinc level in American women, there was no significant difference in the parameters of plasma zinc and rapid exchange zinc pool in South Korean women. The rate of zinc and zinc absorption into the body tissue was low in South Korean women. Korean women have lower total zinc levels than American women.