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大白鼠84只,分为7组,每组平均体重202—238克,以两肾包膜法形成高血压,在手术前或次日起分别给以酸枣仁(20—30克/公斤/日,自由取食)、野菊花(10克/公斤/日)、芹菜(自由取食)、延胡索乙素(20毫克/公斤/日)、氢氯噻嗪(0.1克/公斤/日)、溴苄乙铵(10毫克/公斤/日)6种药物。用鼠尾容积法测量收缩压,以手术后第2周升压总值(各鼠每日收缩压升高毫米汞柱数之总和)与对照组比较,酸枣仁对大白鼠肾型高血压的形成有抑制作用,其余5药则无显著作用。
Eighty-four rats were divided into 7 groups, each weighing 202-238g on average. Two renal capsule methods were used to induce hypertension. The rats were given sucralose (20-30 g / kg / day) , Chrysanthemum (10 g / kg / day), celery (fed freely), tetrahydropalmatine (20 mg / kg / day), hydrochlorothiazide (0.1 g / kg / day) (10 mg / kg / day) six kinds of drugs. Systolic blood pressure was measured by rat tail volume method. Compared with the control group, the total value of blood pressure in the second week after operation (the sum of the daily milliliters of systolic blood pressure in each rat) The formation of an inhibitory effect, the remaining 5 drugs have no significant effect.