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目的:评价唾液抗幽门螺杆菌(Hp)抗体诊断Hp感染的价值。方法93例病人同时进行唾液抗HpIgG测定、快速尿素酶试验(RUT)、组织涂片HE染色及病理WS银染色法诊断Hp感染。结果唾液抗HPIgG检测阳性率近似于RUT法(P>0.05),高于组织涂片HE染色法和病理WS银染色法(P<0.01)。其诊断Hp感染的敏感性为96.97%,特异性88.23%,准确性95.18%,阳性预测值96.97%,阴性预测值88.24%。结论唾液抗HPIgG检测是诊断Hp感染的敏感性指标。
Objective: To evaluate the value of salivary anti-Helicobacter pylori (Hp) antibody in the diagnosis of Hp infection. Methods Ninety-three patients were tested for anti-HpIgG, rapid urease test (RUT), tissue smear HE staining and pathological WS silver staining for Hp infection. Results The positive rate of saliva anti-HPIgG was similar to that of RUT (P> 0.05), higher than that of histological stain HE staining and pathological WS silver staining (P <0.01). The diagnosis of Hp infection was 96.97%, specificity 88.23%, accuracy 95.18%, positive predictive value 96.97%, negative predictive value 88.24%. Conclusion Salivary anti-HPIgG test is a sensitive indicator of Hp infection.