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目的:总结应用子宫颈电圈切除术(LEEP)诊断及治疗子宫颈上皮内瘤样变(CIN)的近期效果,探讨病变持续存在及复发的因素。方法:对256例CIN2,3患者应用LEEP术,术后进行阴道镜及细胞学复查。结果:CIN2,3共237例,治愈226例,治愈率为95.4%;宫颈病变持续存在11例,为4.6%,其中手术切缘无病变累及者6例,有病变累及者5例;发生手术并发症8例,为3.1%;术后复发8例;手术切缘有无病变累及者各4例。LEEP术切除组织中无CIN病变者18例,为7.6%。术后确诊为宫颈微小浸润癌11例。结论:应用LEEP术诊治CIN的疗效较高,并可用于微小浸润癌的诊断。手术切缘有病变累及是CIN病变持续存在的因素。
OBJECTIVE: To summarize the short-term results of cervical electrocautery excision (LEEP) diagnosis and treatment of cervical intraepithelial neoplasia (CIN) and to explore the persistence and recurrence of lesions. Methods: 256 cases of CIN2,3 patients with LEEP surgery, postoperative colposcopy and cytological review. Results: A total of 237 CIN2,3 cases were cured, 226 cases were cured, the cure rate was 95.4%. Cervical lesions persisted in 11 cases (4.6%), of which 6 cases had no surgical involvement and 5 cases had lesions Cases; surgical complications occurred in 8 cases, 3.1%; 8 cases of recurrence; surgical margins of lesions in 4 cases. LEEP surgical resection of the organization without CIN lesions in 18 cases, 7.6%. Postoperative diagnosis of cervical micro-invasive carcinoma in 11 cases. Conclusion: The clinical application of LEEP in the diagnosis and treatment of CIN is more effective and can be used for the diagnosis of micro-invasive carcinoma. Surgical margins have lesion involvement is a persistent factor in CIN lesions.