蛋白酶抑制剂(PI)是一类具有抗逆转录病毒活性的新药。目前,规范的抗HIV感染的治疗方案是由一种PI和两种核苷类似物所组成,但此类药物有某些副作用,其中有引起重症肝炎的记载。作者报道了一例由沙奎那韦、利托那韦和斯塔夫定治疗后发生的肝炎病例,但在改用斯塔夫定、拉米夫定和 Protease inhibitors (PIs) are a class of new anti-retroviral drugs. At present, the standard treatment scheme for anti-HIV infection consists of a PI and two nucleoside analogues, but such drugs have certain side effects, among which is a record of causing severe hepatitis. The authors reported a case of hepatitis that occurred after treatment with saquinavir, ritonavir, and stavudine, but switched to stavudine, lamivudine and