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美《医学论坛》第23卷第1期(1982年)报道:弥漫性血管内凝血(DIC)疾病的特征是凝血系统具有不适当的激活作用,随之,体内的血纤维蛋白原转变为血纤维蛋白也发生了改变。虽然在病程中的出血现象已被广泛认识,但血栓形成也具有同等的重要性。病人可能出现手足发绀、日周发绀、指(趾)梗塞和器官功能衰竭,最常见的是肾和肝功能衰竭。 DIC过程中的一部分表现是溶纤维蛋白系统的过度激活,结果是纤维蛋白降解为不同的小型产物,当这种消耗过程超过凝血因子的合成率和血小板的产生率时,这些成分的水平减
Volume 23, Number 1 (1982) by the United States Medical Tribune: Diffuse intravascular coagulation (DIC) disease is characterized by an inappropriate activation of the coagulation system, followed by an in vivo conversion of fibrinogen to blood Fibrin also changed. Although hemorrhage in the course of the disease has been widely recognized, but also have the same importance of thrombosis. Patients may experience cyanosis of hands and feet, cyanosis of the week, infarcts of the fingers and organ failure, the most common being renal and hepatic failure. Part of the DIC process is an over-activation of the fibrin system, with the result that fibrin degrades into smaller, smaller products, and when this consumption exceeds the rate of clotting factor synthesis and platelet production, the levels of these components decrease